KRT75 and WASHC1

Data Source:
BioGRID (two hybrid)

		KRT75	WASHC1
Description		keratin 75	WASH complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex
	Molecular Function	Structural Molecule Activity Protein Binding	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Keratinization Cornification	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Pseudofolliculitis barbae
GWAS
Interacting Genes		124 interacting genes: ABI2 AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf109 C1orf216 C2CD6 CAMK2A CARD10 CARD9 CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DES DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT3 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C PRPH RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 U2AF1L5 USHBP1 VIM WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT	54 interacting genes: ABI2 ABI3 ATPAF2 BECN1 BLOC1S2 C14orf119 C1orf216 CDR2L CEP55 EIF3F EXOC8 FHL2 GYS1 HGS HSBP1 HSF2BP IFT57 KANK2 KLC3 KRT20 KRT26 KRT28 KRT3 KRT75 KRT76 LIMK1 LMO1 LMO2 LMO3 LMO4 MORN4 MRFAP1 NDC80 NUP62CL OIP5 OSTF1 POLR1C PRKAA2 RABGEF1 RNF2 SDCBP SMARCD1 TPM1 TPM3 TRIM69 TSG101 TTC19 TXLNA UBL5 USP20 WASHC3 WASHC4 WASHC5 ZBTB16
Entrez ID		9119	100287171
HPRD ID		11057
Ensembl ID		ENSG00000170454	ENSG00000181404
Uniprot IDs		O95678	A8K0Z3
PDB IDs
Enriched GO Terms of Interacting Partners?
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