WASHC1 and KRT28

Data Source:
BioGRID (two hybrid)

		WASHC1	KRT28
Description		WASH complex subunit 1	keratin 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane	Biological_process Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872) Glucose homeostasis traits ( 25524916)
Interacting Genes		54 interacting genes: ABI2 ABI3 ATPAF2 BECN1 BLOC1S2 C14orf119 C1orf216 CDR2L CEP55 EIF3F EXOC8 FHL2 GYS1 HGS HSBP1 HSF2BP IFT57 KANK2 KLC3 KRT20 KRT26 KRT28 KRT3 KRT75 KRT76 LIMK1 LMO1 LMO2 LMO3 LMO4 MORN4 MRFAP1 NDC80 NUP62CL OIP5 OSTF1 POLR1C PRKAA2 RABGEF1 RNF2 SDCBP SMARCD1 TPM1 TPM3 TRIM69 TSG101 TTC19 TXLNA UBL5 USP20 WASHC3 WASHC4 WASHC5 ZBTB16	19 interacting genes: ABI3 CCDC196 DEUP1 KRT1 KRT3 KRT4 KRT5 KRT6A KRT6B KRT71 KRT79 KRT8 KRT80 KRT81 KRT86 NUP58 UCHL5 USHBP1 WASHC1
Entrez ID		100287171	162605
HPRD ID			17245
Ensembl ID		ENSG00000181404	ENSG00000173908
Uniprot IDs		A8K0Z3	Q7Z3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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