WASHC1 and KRT3

Data Source:
BioGRID (two hybrid)

		WASHC1	KRT3
Description		WASH complex subunit 1	keratin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding	Protein Binding
	Biological Process	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Meesmann corneal dystrophy
GWAS
Interacting Genes		54 interacting genes: ABI2 ABI3 ATPAF2 BECN1 BLOC1S2 C14orf119 C1orf216 CDR2L CEP55 EIF3F EXOC8 FHL2 GYS1 HGS HSBP1 HSF2BP IFT57 KANK2 KLC3 KRT20 KRT26 KRT28 KRT3 KRT75 KRT76 LIMK1 LMO1 LMO2 LMO3 LMO4 MORN4 MRFAP1 NDC80 NUP62CL OIP5 OSTF1 POLR1C PRKAA2 RABGEF1 RNF2 SDCBP SMARCD1 TPM1 TPM3 TRIM69 TSG101 TTC19 TXLNA UBL5 USP20 WASHC3 WASHC4 WASHC5 ZBTB16	40 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT14 KRT16 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT75 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426
Entrez ID		100287171	3850
HPRD ID			01013
Ensembl ID		ENSG00000181404	ENSG00000186442
Uniprot IDs		A8K0Z3	P12035
PDB IDs
Enriched GO Terms of Interacting Partners?
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