KRT75 and KCTD7

Data Source:
BioGRID (two hybrid)

		KRT75	KCTD7
Description		keratin 75	potassium channel tetramerization domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Keratinization Cornification	Positive Regulation Of Transporter Activity Post-translational Protein Modification Protein Homooligomerization Membrane Hyperpolarization Glutamate Homeostasis
Pathways		Keratinization Formation of the cornified envelope	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Pseudofolliculitis barbae
GWAS			Aortic root size ( 21223598) Cotinine glucuronidation ( 25293881) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		124 interacting genes: ABI2 AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf109 C1orf216 C2CD6 CAMK2A CARD10 CARD9 CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DES DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT3 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C PRPH RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 U2AF1L5 USHBP1 VIM WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT	41 interacting genes: ADAMTSL4 ATXN7L2 BAG4 CUL3 DVL3 EFHC2 GAS2L2 GORASP2 INCA1 INO80B KAT5 KRT75 KRTAP13-3 LNX1 MDFI MEOX1 MEOX2 NIF3L1 NTAQ1 NXF1 PARVG PAX6 PIN1 PPARA PRPF18 PRR22 PSMA1 RAB4A REL TCEA2 TCEANC TERF1 TRIM2 TRIM3 UBC VEZF1 ZNF417 ZNF438 ZNF474 ZNF552 ZNF587
Entrez ID		9119	154881
HPRD ID		11057	13770
Ensembl ID		ENSG00000170454	ENSG00000243335
Uniprot IDs		O95678	A0A024RDN7 Q96MP8
PDB IDs
Enriched GO Terms of Interacting Partners?
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