ATP6V0D1 and TLX3

Data Source:
BioGRID (two hybrid)

		ATP6V0D1	TLX3
Description		ATPase H+ transporting V0 subunit d1	T cell leukemia homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Centrosome Endosome Membrane Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cellular Iron Ion Homeostasis Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels IRE1-mediated Unfolded Protein Response Cilium Assembly Phagosome Acidification Proton Transmembrane Transport	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Neuron Differentiation Animal Organ Development Neuron Fate Specification
Pathways		ROS and RNS production in phagocytes XBP1(S) activates chaperone genes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Blood protein levels ( 28240269) Disease progression in age-related macular degeneration ( 29346644) Empathy quotient ( 29527006) Medication use (thyroid preparations) ( 31015401) Refractive error ( 32231278)	Body size at age 10 ( 32376654)
Interacting Genes		10 interacting genes: ADRB2 ATXN1 DMRT3 GATA1 IHO1 IKZF3 LIG4 RBPMS TLE5 TLX3	106 interacting genes: ACY1 AKAP9 ANKRD10 ANKRD33 AOC1 APBB1IP ARMC5 ASB12 ATP6V0D1 B9D2 BPIFA1 C11orf1 C11orf45 C19orf54 C2orf42 CEACAM6 CRX CSNK2B CTNNA3 DENND4A EFEMP2 ERAS FAM166B FAM168B FCSK FNTB FOSB FOXH1 GGTLC2 GOLGA6L9 GTF2A1L H2BC11 HNRNPUL1 HOPX HSPB2 HSPB2-C11orf52 HYI IGFL2 ING4 INTS11 IRF9 ITIH6 KRT34 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP19-7 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LMO2 MAGED1 MEIS1 METTL27 MORN5 MSX2 NDUFAB1 NHLRC4 NICN1 OIP5 PLA2G10 PLAAT1 POU2AF1 POU6F2 PPP1CC PQBP1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB11 REL ROR2 RSKR SERPINE1 SLC15A2 SMU1 SNTA1 SP1 SPATA46 SPRYD7 STH SYNGAP1 TBX22 TCIRG1 TEKT5 TEX37 THTPA TLE1 TLE2 TMEM42 TOX2 TP53BP1 TRIM42 UFSP1 WDR83 YPEL3 ZBTB32 ZNF34 ZNF41 ZNF44
Entrez ID		9114	30012
HPRD ID		06121	06868
Ensembl ID		ENSG00000159720	ENSG00000164438
Uniprot IDs		P61421 R4GN72	O43711
PDB IDs
Enriched GO Terms of Interacting Partners?
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