Description |
T cell leukemia homeobox 3 |
farnesyltransferase, CAAX box, beta |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- AZD3409
- Tipifarnib
- Lonafarnib
- 2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE
- (11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE
- L-778123
- [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
- Farnesyl diphosphate
- Geranylgeranyl diphosphate
- ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
- (20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE
- (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE
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Diseases |
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GWAS |
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Interacting Genes |
106 interacting genes:
ACY1
AKAP9
ANKRD10
ANKRD33
AOC1
APBB1IP
ARMC5
ASB12
ATP6V0D1
B9D2
BPIFA1
C11orf1
C11orf45
C19orf54
C2orf42
CEACAM6
CRX
CSNK2B
CTNNA3
DENND4A
EFEMP2
ERAS
FAM166B
FAM168B
FCSK
FNTB
FOSB
FOXH1
GGTLC2
GOLGA6L9
GTF2A1L
H2BC11
HNRNPUL1
HOPX
HSPB2
HSPB2-C11orf52
HYI
IGFL2
ING4
INTS11
IRF9
ITIH6
KRT34
KRTAP11-1
KRTAP13-3
KRTAP19-1
KRTAP19-7
KRTAP3-1
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
LASP1
LMO2
MAGED1
MEIS1
METTL27
MORN5
MSX2
NDUFAB1
NHLRC4
NICN1
OIP5
PLA2G10
PLAAT1
POU2AF1
POU6F2
PPP1CC
PQBP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMB11
REL
ROR2
RSKR
SERPINE1
SLC15A2
SMU1
SNTA1
SP1
SPATA46
SPRYD7
STH
SYNGAP1
TBX22
TCIRG1
TEKT5
TEX37
THTPA
TLE1
TLE2
TMEM42
TOX2
TP53BP1
TRIM42
UFSP1
WDR83
YPEL3
ZBTB32
ZNF34
ZNF41
ZNF44
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17 interacting genes:
AGXT
APOL6
ATPAF2
CCDC24
CENPF
FNTA
GBP1
HDAC6
HOXC8
HRAS
KRAS
KRBA1
PTP4A3
RAP2A
RRAS2
SMG9
TLX3
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Entrez ID |
30012 |
2342 |
HPRD ID |
06868 |
00608 |
Ensembl ID |
ENSG00000164438
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ENSG00000257365
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Uniprot IDs |
O43711
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A0A384MEJ5
P49356
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PDB IDs |
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1JCQ
1LD7
1LD8
1MZC
1S63
1SA4
1TN6
2F0Y
2H6F
2H6G
2H6H
2H6I
2IEJ
3E37
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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