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TLX3 and THTPA
Data Source:
BioGRID
(two hybrid)
TLX3
THTPA
Description
T cell leukemia homeobox 3
thiamine triphosphatase
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Magnesium Ion Binding
Protein Binding
Hydrolase Activity
Thiamin-triphosphatase Activity
Biological Process
Neuron Migration
Regulation Of Respiratory Gaseous Exchange By Nervous System Process
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Respiratory Gaseous Exchange By Respiratory System
Negative Regulation Of Neuron Differentiation
Animal Organ Development
Neuron Fate Specification
Generation Of Precursor Metabolites And Energy
Thiamine Metabolic Process
Dephosphorylation
Thiamine Diphosphate Metabolic Process
Thiamine-containing Compound Metabolic Process
Pathways
Vitamin B1 (thiamin) metabolism
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS
Body size at age 10 (
32376654
)
Interacting Genes
106 interacting genes:
ACY1
AKAP9
ANKRD10
ANKRD33
AOC1
APBB1IP
ARMC5
ASB12
ATP6V0D1
B9D2
BPIFA1
C11orf1
C11orf45
C19orf54
C2orf42
CEACAM6
CRX
CSNK2B
CTNNA3
DENND4A
EFEMP2
ERAS
FAM166B
FAM168B
FCSK
FNTB
FOSB
FOXH1
GGTLC2
GOLGA6L9
GTF2A1L
H2BC11
HNRNPUL1
HOPX
HSPB2
HSPB2-C11orf52
HYI
IGFL2
ING4
INTS11
IRF9
ITIH6
KRT34
KRTAP11-1
KRTAP13-3
KRTAP19-1
KRTAP19-7
KRTAP3-1
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
LASP1
LMO2
MAGED1
MEIS1
METTL27
MORN5
MSX2
NDUFAB1
NHLRC4
NICN1
OIP5
PLA2G10
PLAAT1
POU2AF1
POU6F2
PPP1CC
PQBP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMB11
REL
ROR2
RSKR
SERPINE1
SLC15A2
SMU1
SNTA1
SP1
SPATA46
SPRYD7
STH
SYNGAP1
TBX22
TCIRG1
TEKT5
TEX37
THTPA
TLE1
TLE2
TMEM42
TOX2
TP53BP1
TRIM42
UFSP1
WDR83
YPEL3
ZBTB32
ZNF34
ZNF41
ZNF44
1 interacting genes:
TLX3
Entrez ID
30012
79178
HPRD ID
06868
15505
Ensembl ID
ENSG00000164438
ENSG00000259431
Uniprot IDs
O43711
G3V5Q5
Q9BU02
PDB IDs
3BHD
3TVL
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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