CCT6A and PARP4

Data Source:
BioGRID (two hybrid)

		CCT6A	PARP4
Description		chaperonin containing TCP1 subunit 6A	poly(ADP-ribose) polymerase family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Extracellular Exosome	Nucleus Cytoplasm Cytosol Spindle Microtubule Membrane Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding WD40-repeat Domain Binding	DNA Binding NAD+ ADP-ribosyltransferase Activity Protein Binding Enzyme Binding Protein ADP-ribosylase Activity
	Biological Process	Protein Folding Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	DNA Repair Cellular Protein Modification Process Protein ADP-ribosylation Inflammatory Response Cellular Response To DNA Damage Stimulus Cell Death Response To Drug Regulation Of Telomerase Activity Protein Mono-ADP-ribosylation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Nicotinamide salvaging Maturation of nucleoprotein Maturation of nucleoprotein
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31015462) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Systolic blood pressure ( 30224653)	Idiopathic intracranial hypertension ( 29608535) Obesity-related traits ( 23251661) Sudden cardiac arrest ( 21658281)
Interacting Genes		15 interacting genes: DUX4 ERCC6 IMPA2 KDM5A LINC01554 MLX MYBPC2 PARP4 PTEN SGCG SUMO2 SUMO4 SUPT16H TRIM31 TTN	3 interacting genes: CCT6A MVP SMAD3
Entrez ID		908	143
HPRD ID		00089	09598
Ensembl ID		ENSG00000146731	ENSG00000102699
Uniprot IDs		A0A024RDL1 P40227	Q9UKK3
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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