PARP4 and CCT6A

Data Source:
BioGRID (two hybrid)

		PARP4	CCT6A
Description		poly(ADP-ribose) polymerase family member 4	chaperonin containing TCP1 subunit 6A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Spindle Microtubule Membrane Extracellular Exosome Ribonucleoprotein Complex	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Extracellular Exosome
	Molecular Function	DNA Binding NAD+ ADP-ribosyltransferase Activity Protein Binding Enzyme Binding Protein ADP-ribosylase Activity	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding WD40-repeat Domain Binding
	Biological Process	DNA Repair Cellular Protein Modification Process Protein ADP-ribosylation Inflammatory Response Cellular Response To DNA Damage Stimulus Cell Death Response To Drug Regulation Of Telomerase Activity Protein Mono-ADP-ribosylation	Protein Folding Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Nicotinamide salvaging Maturation of nucleoprotein Maturation of nucleoprotein	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS		Idiopathic intracranial hypertension ( 29608535) Obesity-related traits ( 23251661) Sudden cardiac arrest ( 21658281)	Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31015462) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Systolic blood pressure ( 30224653)
Interacting Genes		3 interacting genes: CCT6A MVP SMAD3	15 interacting genes: DUX4 ERCC6 IMPA2 KDM5A LINC01554 MLX MYBPC2 PARP4 PTEN SGCG SUMO2 SUMO4 SUPT16H TRIM31 TTN
Entrez ID		143	908
HPRD ID		09598	00089
Ensembl ID		ENSG00000102699	ENSG00000146731
Uniprot IDs		Q9UKK3	A0A024RDL1 P40227
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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