CCT6A and MYBPC2

Data Source:
BioGRID (two hybrid)

		CCT6A	MYBPC2
Description		chaperonin containing TCP1 subunit 6A	myosin binding protein C2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Extracellular Exosome	Cytosol Myosin Filament
	Molecular Function	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding WD40-repeat Domain Binding	Actin Binding Protein Binding Structural Constituent Of Muscle
	Biological Process	Protein Folding Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	Cell Adhesion Muscle Filament Sliding
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Striated Muscle Contraction
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31015462) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Systolic blood pressure ( 30224653)	Primary biliary cholangitis ( 26394269)
Interacting Genes		15 interacting genes: DUX4 ERCC6 IMPA2 KDM5A LINC01554 MLX MYBPC2 PARP4 PTEN SGCG SUMO2 SUMO4 SUPT16H TRIM31 TTN	31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3
Entrez ID		908	4606
HPRD ID		00089	01184
Ensembl ID		ENSG00000146731	ENSG00000086967
Uniprot IDs		A0A024RDL1 P40227	A0A140VJQ0 Q14324
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8	2E7C 2EDK 2EDN
Enriched GO Terms of Interacting Partners?
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