ATP6V0E1 and ATP6V1E1

Data Source:
HPRD (two hybrid)

		ATP6V0E1	ATP6V1E1
Description		ATPase H+ transporting V0 subunit e1	ATPase H+ transporting V1 subunit E1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Exosome
	Molecular Function	Protein Binding Hydrolase Activity ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Hydrolase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS		Body mass index ( 27455349) PR interval ( 32439900)
Interacting Genes		19 interacting genes: - APOD ATP6V1E1 CDIPT COL8A2 CXCL16 EMP1 GPR25 KIR2DL3 MAL2 MS4A13 MS4A4A NAT8 OPRM1 PLN SYT15 TMEM218 TMEM254 YIPF6	14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD SLC9A3R1 SOS1 TRAF6 XRCC6
Entrez ID		8992	529
HPRD ID		04894	00163
Ensembl ID		ENSG00000113732	ENSG00000131100
Uniprot IDs		O15342	P36543 Q53Y06
PDB IDs
Enriched GO Terms of Interacting Partners?
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