KLHL6 and RC3H2

Data Source:
BioGRID (enzymatic study, pull down, pull down, affinity chromatography technology)

		KLHL6	RC3H2
Description		kelch like family member 6	ring finger and CCCH-type domains 2
Image		No pdb structure
GO Annotations	Cellular Component		P-body Cell Surface Cytoplasmic Stress Granule Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	DNA Binding RNA Binding Double-stranded RNA Binding MRNA Binding RNA Stem-loop Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Germinal Center Formation B Cell Receptor Signaling Pathway	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay B Cell Homeostasis Ubiquitin-dependent Protein Catabolic Process Post-embryonic Development Multicellular Organism Growth T Cell Proliferation T Cell Homeostasis Regulation Of MRNA Stability Lung Alveolus Development Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Limb Development T Follicular Helper Cell Differentiation Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Youthful appearance (self-reported) ( 32339537)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: BYSL CRY2 FH PPP1R1B RC3H2 SBDS TMPO	14 interacting genes: KLHL6 TRIM8 UBC UBE2B UBE2D2 UBE2E2 UBE2E3 UBE2G2 UBE2I UBE2K UBE2N UBE2Q2 UBE2V1 UBE2V2
Entrez ID		89857	54542
HPRD ID		10035	14726
Ensembl ID		ENSG00000172578	ENSG00000056586
Uniprot IDs		Q8WZ60	A0A024R899 Q9HBD1
PDB IDs			4Z30 4Z31 4ZLC 4ZLD
Enriched GO Terms of Interacting Partners?
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