KLHL6 and SBDS

Data Source:
BioGRID (two hybrid)

		KLHL6	SBDS
Description		kelch like family member 6	SBDS ribosome maturation factor
Image		No pdb structure
GO Annotations	Cellular Component		Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Protein Binding	RNA Binding Protein Binding Microtubule Binding RRNA Binding Ribosome Binding
	Biological Process	Germinal Center Formation B Cell Receptor Signaling Pathway	Inner Cell Mass Cell Proliferation Hematopoietic Progenitor Cell Differentiation RRNA Processing Mitotic Spindle Organization Bone Mineralization Leukocyte Chemotaxis Mature Ribosome Assembly Bone Marrow Development
Pathways
Drugs
Diseases			Shwachman-Diamond syndrome (SDS) Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD) Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Youthful appearance (self-reported) ( 32339537)
Interacting Genes		7 interacting genes: BYSL CRY2 FH PPP1R1B RC3H2 SBDS TMPO	8 interacting genes: ACD CLN3 EFL1 KLHL6 LMNA POT1 TERF1 TERF2IP
Entrez ID		89857	51119
HPRD ID		10035	07393
Ensembl ID		ENSG00000172578	ENSG00000126524
Uniprot IDs		Q8WZ60	A0A0S2Z5I7 Q9Y3A5
PDB IDs			2KDO 2L9N 5AN9 5ANB 5ANC 6QKL
Enriched GO Terms of Interacting Partners?
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