RC3H2 and UBE2G2

Data Source:
BioGRID (pull down)

		RC3H2	UBE2G2
Description		ring finger and CCCH-type domains 2	ubiquitin conjugating enzyme E2 G2
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GO Annotations	Cellular Component	P-body Cell Surface Cytoplasmic Stress Granule Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding MRNA Binding RNA Stem-loop Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay B Cell Homeostasis Ubiquitin-dependent Protein Catabolic Process Post-embryonic Development Multicellular Organism Growth T Cell Proliferation T Cell Homeostasis Regulation Of MRNA Stability Lung Alveolus Development Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Limb Development T Follicular Helper Cell Differentiation Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: KLHL6 TRIM8 UBC UBE2B UBE2D2 UBE2E2 UBE2E3 UBE2G2 UBE2I UBE2K UBE2N UBE2Q2 UBE2V1 UBE2V2	39 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		54542	7327
HPRD ID		14726	04387
Ensembl ID		ENSG00000056586	ENSG00000184787
Uniprot IDs		A0A024R899 Q9HBD1	P60604
PDB IDs		4Z30 4Z31 4ZLC 4ZLD	2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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