RC3H2 and KLHL6

Data Source:
BioGRID (enzymatic study, pull down, pull down, affinity chromatography technology)

		RC3H2	KLHL6
Description		ring finger and CCCH-type domains 2	kelch like family member 6
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cell Surface Cytoplasmic Stress Granule Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding MRNA Binding RNA Stem-loop Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay B Cell Homeostasis Ubiquitin-dependent Protein Catabolic Process Post-embryonic Development Multicellular Organism Growth T Cell Proliferation T Cell Homeostasis Regulation Of MRNA Stability Lung Alveolus Development Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Limb Development T Follicular Helper Cell Differentiation Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process	Germinal Center Formation B Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)	Youthful appearance (self-reported) ( 32339537)
Interacting Genes		14 interacting genes: KLHL6 TRIM8 UBC UBE2B UBE2D2 UBE2E2 UBE2E3 UBE2G2 UBE2I UBE2K UBE2N UBE2Q2 UBE2V1 UBE2V2	7 interacting genes: BYSL CRY2 FH PPP1R1B RC3H2 SBDS TMPO
Entrez ID		54542	89857
HPRD ID		14726	10035
Ensembl ID		ENSG00000056586	ENSG00000172578
Uniprot IDs		A0A024R899 Q9HBD1	Q8WZ60
PDB IDs		4Z30 4Z31 4ZLC 4ZLD
Enriched GO Terms of Interacting Partners?
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