AP3D1 and RUFY1

Data Source:
BioGRID (pull down, affinity chromatography technology)

		AP3D1	RUFY1
Description		adaptor related protein complex 3 subunit delta 1	RUN and FYVE domain containing 1
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane AP-3 Adaptor Complex Terminal Bouton Postsynapse Presynaptic Endosome Glutamatergic Synapse Axon Cytoplasm	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Protein Targeting To Vacuole Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Height ( 28552196 31562340) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Myocardial infarction ( 24916648) Pulse pressure ( 30578418) Red blood cell count ( 32888494 27863252) Systolic blood pressure ( 30578418)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		12 interacting genes: AP3B1 AP3S1 AP3S2 ARF1 ARF6 CCN2 CDC42 DUX4 RUFY1 SLC30A3 VAMP7 VPS41	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		8943	80230
HPRD ID		06260	15282
Ensembl ID		ENSG00000065000	ENSG00000176783
Uniprot IDs		O14617	A8K7B1 Q96T51
PDB IDs		4AFI	2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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