AP3D1 and VPS41

Data Source:
HPRD (in vitro, in vivo)

		AP3D1	VPS41
Description		adaptor related protein complex 3 subunit delta 1	VPS41 subunit of HOPS complex
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane AP-3 Adaptor Complex Terminal Bouton Postsynapse Presynaptic Endosome Glutamatergic Synapse Axon Cytoplasm	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding
	Biological Process	Protein Targeting To Vacuole Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport
Pathways
Drugs
Diseases
GWAS		Height ( 28552196 31562340) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Myocardial infarction ( 24916648) Pulse pressure ( 30578418) Red blood cell count ( 32888494 27863252) Systolic blood pressure ( 30578418)	Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)
Interacting Genes		12 interacting genes: AP3B1 AP3S1 AP3S2 ARF1 ARF6 CCN2 CDC42 DUX4 RUFY1 SLC30A3 VAMP7 VPS41	12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B
Entrez ID		8943	27072
HPRD ID		06260	10402
Ensembl ID		ENSG00000065000	ENSG00000006715
Uniprot IDs		O14617	P49754
PDB IDs		4AFI
Enriched GO Terms of Interacting Partners?
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