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CCNB1 and TULP3
Data Source:
BioGRID
(two hybrid)
CCNB1
TULP3
Description
cyclin B1
TUB like protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Cyclin-dependent Protein Kinase Holoenzyme Complex
Spindle Pole
Condensed Nuclear Chromosome Outer Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Matrix
Centrosome
Cytosol
Membrane
Cyclin B1-CDK1 Complex
Extracellular Region
Nucleus
Nucleoplasm
Nucleolus
Plasma Membrane
Cilium
Axoneme
Ciliary Base
9+0 Non-motile Cilium
Molecular Function
Patched Binding
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Ubiquitin-like Protein Ligase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
G Protein-coupled Receptor Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Enzyme Binding
Phosphatidylinositol Binding
Protein-containing Complex Binding
Intraciliary Transport Particle A Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G2/M Transition Of Mitotic Cell Cycle
Oocyte Maturation
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Transcription Initiation From RNA Polymerase II Promoter
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Mitotic Spindle Organization
Mitotic Nuclear Envelope Disassembly
Mitotic Metaphase Plate Congression
Spermatogenesis
Response To Mechanical Stimulus
Negative Regulation Of Gene Expression
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of MRNA 3'-end Processing
Positive Regulation Of Histone Phosphorylation
Tissue Regeneration
Response To Drug
Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Mitotic Cell Cycle
Response To DDT
Positive Regulation Of Fibroblast Proliferation
Digestive Tract Development
Cell Division
Regulation Of Cell Cycle
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Ventricular Cardiac Muscle Cell Development
Positive Regulation Of Cardiac Muscle Cell Proliferation
Regulation Of Chromosome Condensation
Protein-containing Complex Assembly
Cellular Response To Iron(III) Ion
Cellular Response To Fatty Acid
Cellular Response To Organic Cyclic Compound
Cellular Response To Hypoxia
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
Histone H3-S10 Phosphorylation Involved In Chromosome Condensation
Neural Tube Closure
Regulation Of Transcription, DNA-templated
G Protein-coupled Receptor Signaling Pathway
Brain Development
Regulation Of G Protein-coupled Receptor Signaling Pathway
Anterior/posterior Pattern Specification
Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Central Nervous System Neuron Differentiation
Embryonic Camera-type Eye Development
Embryonic Digit Morphogenesis
Negative Regulation Of Smoothened Signaling Pathway
Embryonic Neurocranium Morphogenesis
Bone Development
Bronchus Morphogenesis
Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Protein Localization To Cilium
Ganglion Development
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways
E2F-enabled inhibition of pre-replication complex formation
Polo-like kinase mediated events
Golgi Cisternae Pericentriolar Stack Reorganization
APC/C:Cdc20 mediated degradation of Cyclin B
Regulation of APC/C activators between G1/S and early anaphase
Phosphorylation of the APC/C
Phosphorylation of Emi1
Condensation of Prophase Chromosomes
MASTL Facilitates Mitotic Progression
Resolution of Sister Chromatid Cohesion
Condensation of Prometaphase Chromosomes
Regulation of PLK1 Activity at G2/M Transition
Activation of NIMA Kinases NEK9, NEK6, NEK7
Initiation of Nuclear Envelope (NE) Reformation
Nuclear Pore Complex (NPC) Disassembly
Depolymerisation of the Nuclear Lamina
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Mitotic Prophase
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
The role of GTSE1 in G2/M progression after G2 checkpoint
Transcriptional regulation by RUNX2
Hedgehog 'off' state
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
59 interacting genes:
ANAPC11
ARID4A
BRCA1
CCNB1IP1
CCNF
CDC20
CDC25A
CDC25C
CDC27
CDC34
CDC6
CDK1
CDKN1A
CDKN1B
CDT1
EP300
FLNA
FZR1
GADD45A
GADD45B
GADD45G
H1-1
H1-5
HERC5
ITPR1
KAT5
MAP4
MEF2C
MOK
OTUD7B
PBK
PCNA
PIN1
PKMYT1
PLK1
POLA1
PRC1
PRKDC
PRKN
PTCH1
PTMA
RALBP1
RB1
RPA1
RUNX2
SQSTM1
TGFBR2
TP53BP1
TP73
TSC1
TSPYL2
TULP3
UBE2C
UBE2D2
UBE2N
UBE2S
UBE3C
UBE3D
XIAP
63 interacting genes:
ACTN2
AKAP9
ANKRD1
ANKRD54
ARHGAP21
ARMCX2
ATP2A1
BACH2
BOC
BRMS1L
BTBD1
CCNB1
CHD2
CLIP4
DNTTIP2
DROSHA
DST
ESRRG
GPATCH2L
GSE1
HSF2BP
KIF3A
KLF10
KRTAP10-1
KRTAP10-5
KRTAP10-7
MAGEA6
MAP3K5
MBTD1
MGA
MORF4L1
MYBPC2
MYH3
MYH7
MYO18B
NCOR1
NFE2L1
NOSTRIN
NRIP1
PAF1
PCGF6
PDE4DIP
PHAX
PRKAR1A
PSTPIP1
RCOR3
RIOK3
RNF10
ROPN1
RYR1
SLAIN2
SPTB
SRP72
TNNT1
TNNT3
WNK1
ZFAT
ZNF160
ZNF462
ZNF619
ZNF793
ZNF835
ZSCAN23
Entrez ID
891
7289
HPRD ID
00454
05292
Ensembl ID
ENSG00000134057
ENSG00000078246
Uniprot IDs
P14635
B7Z1E7
O75386
PDB IDs
2B9R
2JGZ
4Y72
4YC3
5HQ0
5LQF
6GU2
6GU3
6GU4
Enriched GO Terms of Interacting Partners
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