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TULP3 and NCOR1
Data Source:
BioGRID
(two hybrid)
TULP3
NCOR1
Description
TUB like protein 3
nuclear receptor corepressor 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Nucleolus
Plasma Membrane
Cilium
Axoneme
Ciliary Base
9+0 Non-motile Cilium
Histone Deacetylase Complex
Chromatin
Nucleus
Nucleoplasm
Cytosol
Membrane
Sin3 Complex
Transcription Repressor Complex
Mitotic Spindle
Molecular Function
G Protein-coupled Receptor Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Enzyme Binding
Phosphatidylinositol Binding
Protein-containing Complex Binding
Intraciliary Transport Particle A Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Hormone Receptor Binding
Histone Deacetylase Binding
Thyroid Hormone Receptor Binding
Biological Process
Neural Tube Closure
Regulation Of Transcription, DNA-templated
G Protein-coupled Receptor Signaling Pathway
Brain Development
Regulation Of G Protein-coupled Receptor Signaling Pathway
Anterior/posterior Pattern Specification
Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Central Nervous System Neuron Differentiation
Embryonic Camera-type Eye Development
Embryonic Digit Morphogenesis
Negative Regulation Of Smoothened Signaling Pathway
Embryonic Neurocranium Morphogenesis
Bone Development
Bronchus Morphogenesis
Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Protein Localization To Cilium
Ganglion Development
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Circadian Rhythm
Regulation Of Lipid Metabolic Process
Locomotor Rhythm
Negative Regulation Of Glycolytic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of JNK Cascade
Spindle Assembly
Negative Regulation Of Androgen Receptor Signaling Pathway
Negative Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA
Pathways
Hedgehog 'off' state
Nuclear signaling by ERBB4
Nuclear signaling by ERBB4
NR1D1 (REV-ERBA) represses gene expression
PPARA activates gene expression
PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HDACs deacetylate histones
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by PPARalpha
Circadian Clock
Circadian Clock
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Adult body size (
32376654
)
C-reactive protein levels (
30388399
)
FEV1 (
30804560
)
Free thyroxine concentration (
30367059
)
Lung function (FEV1) (
26635082
)
Lung function (FVC) (
30804560
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Interacting Genes
63 interacting genes:
ACTN2
AKAP9
ANKRD1
ANKRD54
ARHGAP21
ARMCX2
ATP2A1
BACH2
BOC
BRMS1L
BTBD1
CCNB1
CHD2
CLIP4
DNTTIP2
DROSHA
DST
ESRRG
GPATCH2L
GSE1
HSF2BP
KIF3A
KLF10
KRTAP10-1
KRTAP10-5
KRTAP10-7
MAGEA6
MAP3K5
MBTD1
MGA
MORF4L1
MYBPC2
MYH3
MYH7
MYO18B
NCOR1
NFE2L1
NOSTRIN
NRIP1
PAF1
PCGF6
PDE4DIP
PHAX
PRKAR1A
PSTPIP1
RCOR3
RIOK3
RNF10
ROPN1
RYR1
SLAIN2
SPTB
SRP72
TNNT1
TNNT3
WNK1
ZFAT
ZNF160
ZNF462
ZNF619
ZNF793
ZNF835
ZSCAN23
89 interacting genes:
ACTN2
AR
ATXN1
ATXN1L
ATXN3
BCL6
C1D
CBFA2T2
CHD1
CHUK
CLK1
CNOT2
COPS2
CSNK2A1
CXADR
DACH1
DDX20
DHX30
DZIP3
ENO1
ESR1
ESR2
ETS1
ETS2
GPS2
GTF2B
H3C1
H4C1
HDAC3
HDAC5
HDAC9
HESX1
HEY2
HTT
KLF5
MECP2
MYB
MYBL2
MYOD1
NCOA1
NCOA3
NCOR2
NELFE
NR1D1
NR1D2
NR1H2
NR1H3
NR2E3
NR3C1
NR6A1
PDCD2
PHB
PIAS1
PML
POU1F1
PPARA
PPARD
PPARG
PTMA
RARA
RARG
RBPJ
RUNX1
RUNX1T1
RXRA
SAFB
SAP30
SKI
SKIL
SNW1
SP1
SPEN
SQSTM1
SUMO2
TAB2
TAF6
TAF9
TBL1X
TBL1XR1
THRA
THRB
TRIM14
TULP3
TXNRD2
VDR
ZBTB16
ZBTB33
ZBTB7A
ZMYND11
Entrez ID
7289
9611
HPRD ID
05292
02911
Ensembl ID
ENSG00000078246
ENSG00000141027
Uniprot IDs
B7Z1E7
O75386
A0A024RD47
O75376
Q6PGR4
PDB IDs
2EQR
3H52
3KMZ
3N00
4MDD
4WVD
6ONI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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