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TULP3 and MAP3K5
Data Source:
BioGRID
(two hybrid)
TULP3
MAP3K5
Description
TUB like protein 3
mitogen-activated protein kinase kinase kinase 5
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Nucleolus
Plasma Membrane
Cilium
Axoneme
Ciliary Base
9+0 Non-motile Cilium
Cytoplasm
Cytosol
External Side Of Plasma Membrane
Protein-containing Complex
Protein Kinase Complex
IRE1-TRAF2-ASK1 Complex
Molecular Function
G Protein-coupled Receptor Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Enzyme Binding
Phosphatidylinositol Binding
Protein-containing Complex Binding
Intraciliary Transport Particle A Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Protein Phosphatase Binding
Protein Domain Specific Binding
Identical Protein Binding
Protein Homodimerization Activity
Biological Process
Neural Tube Closure
Regulation Of Transcription, DNA-templated
G Protein-coupled Receptor Signaling Pathway
Brain Development
Regulation Of G Protein-coupled Receptor Signaling Pathway
Anterior/posterior Pattern Specification
Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Central Nervous System Neuron Differentiation
Embryonic Camera-type Eye Development
Embryonic Digit Morphogenesis
Negative Regulation Of Smoothened Signaling Pathway
Embryonic Neurocranium Morphogenesis
Bone Development
Bronchus Morphogenesis
Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Protein Localization To Cilium
Ganglion Development
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
MAPK Cascade
Activation Of MAPKK Activity
Response To Ischemia
Protein Phosphorylation
JNK Cascade
Activation Of JUN Kinase Activity
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Viral Process
Cellular Response To Stress
Cellular Response To Amino Acid Starvation
Response To Endoplasmic Reticulum Stress
P38MAPK Cascade
Wound Healing
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of JUN Kinase Activity
Innate Immune Response
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of JNK Cascade
Stress-activated MAPK Cascade
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Cellular Response To Hydrogen Peroxide
Cellular Response To Tumor Necrosis Factor
Endothelial Cell Apoptotic Process
Apoptotic Signaling Pathway
Programmed Necrotic Cell Death
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Neuron Death
Cellular Response To Reactive Nitrogen Species
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Pathways
Hedgehog 'off' state
Oxidative Stress Induced Senescence
Oxidative Stress Induced Senescence
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Eosinophil counts (
32888494
)
HDL cholesterol (
30275531
)
HDL cholesterol levels (
32203549
)
Immature fraction of reticulocytes (
32888494
)
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
63 interacting genes:
ACTN2
AKAP9
ANKRD1
ANKRD54
ARHGAP21
ARMCX2
ATP2A1
BACH2
BOC
BRMS1L
BTBD1
CCNB1
CHD2
CLIP4
DNTTIP2
DROSHA
DST
ESRRG
GPATCH2L
GSE1
HSF2BP
KIF3A
KLF10
KRTAP10-1
KRTAP10-5
KRTAP10-7
MAGEA6
MAP3K5
MBTD1
MGA
MORF4L1
MYBPC2
MYH3
MYH7
MYO18B
NCOR1
NFE2L1
NOSTRIN
NRIP1
PAF1
PCGF6
PDE4DIP
PHAX
PRKAR1A
PSTPIP1
RCOR3
RIOK3
RNF10
ROPN1
RYR1
SLAIN2
SPTB
SRP72
TNNT1
TNNT3
WNK1
ZFAT
ZNF160
ZNF462
ZNF619
ZNF793
ZNF835
ZSCAN23
64 interacting genes:
AKT1
ARRB1
ARRB2
AURKA
CCND2
CDC25A
CDK4
CDK6
CDKN1A
CDKN2A
CREBBP
DAB2IP
DAXX
DMD
DUSP19
EIF2AK2
EP300
ERN1
FGFR4
FZR1
GADD45B
GEMIN5
GLIS2
GLRX
GSTM1
HSPA1A
IGF1R
JAK2
MAP2K4
MAP2K6
MAP2K7
MAP3K2
MAP3K3
MAP3K6
MAP3K7
MAPK8IP3
MBP
NEDD4
NEDD4L
NF2
PDCD6
PPP3R1
PPP5C
PTPN11
QARS1
RAF1
SFN
SIAH1
STK11
TEAD2
TERT
TNFAIP3
TNNT2
TPD52L1
TRAF2
TRAF5
TRAF6
TULP3
TXN
USP9X
YWHAE
YWHAH
YWHAQ
YWHAZ
Entrez ID
7289
4217
HPRD ID
05292
03904
Ensembl ID
ENSG00000078246
ENSG00000197442
Uniprot IDs
B7Z1E7
O75386
Q99683
PDB IDs
2CLQ
3VW6
4BF2
4BHN
4BIB
4BIC
4BID
4BIE
5ULM
5UOR
5UOX
5UP3
5V19
5V24
5VIL
5VIO
6E2M
6E2N
6E2O
6EJL
6OYT
6OYW
6VRE
6XIH
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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