ASAH1

Description		N-acylsphingosine amidohydrolase 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Lysosome Early Endosome Endoplasmic Reticulum Lysosomal Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Fatty Acid Amide Hydrolase Activity Ceramidase Activity
	Biological Process	Fatty Acid Metabolic Process Glycosphingolipid Metabolic Process Keratinocyte Differentiation Neutrophil Degranulation Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Ceramide Catabolic Process Regulation Of Steroid Biosynthetic Process Regulation Of Programmed Necrotic Cell Death Cellular Response To Tumor Necrosis Factor
Pathways		Glycosphingolipid metabolism Neutrophil degranulation
Drugs
Diseases		Farber lipogranulomatosis; Farber disease
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Night sleep phenotypes ( 27126917) Obesity ( 21552555) Type 2 diabetes ( 32499647)
Interacting Genes		6 interacting genes: CAMK1D HSPB2 SETDB1 SMPD1 SRPK1 TSC22D1
Entrez ID		427
HPRD ID		01969
Ensembl ID		ENSG00000104763
Uniprot IDs		A8K0B6 Q13510 Q53H01
PDB IDs		5U7Z 6MHM
Enriched GO Terms of Interacting Partners?
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