CBS and NTAQ1

Data Source:
BioGRID (two hybrid)

		CBS	NTAQ1
Description		cystathionine beta-synthase	N-terminal glutamine amidase 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytosol
	Molecular Function	Cystathionine Beta-synthase Activity Protein Binding Oxygen Binding Enzyme Binding Heme Binding Pyridoxal Phosphate Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Nitrite Reductase (NO-forming) Activity Carbon Monoxide Binding Nitric Oxide Binding Modified Amino Acid Binding S-adenosyl-L-methionine Binding	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Cysteine Biosynthetic Process From Serine L-serine Metabolic Process L-serine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Cysteine Biosynthetic Process Transsulfuration L-cysteine Catabolic Process DNA Protection Homocysteine Catabolic Process Homocysteine Metabolic Process Hydrogen Sulfide Biosynthetic Process	Cellular Protein Modification Process
Pathways		Cysteine formation from homocysteine Cysteine formation from homocysteine Metabolism of ingested SeMet, Sec, MeSec into H2Se
Drugs		Pyridoxal phosphate Ademetionine Serine Cysteine
Diseases		Homocystinuria
GWAS		Blood and toenail selenium levels ( 25343990) Blood metabolite levels ( 24816252) Blood trace element (Se levels) ( 23720494) Homocysteine levels ( 23824729 20031578) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Plasma homocysteine levels (post-methionine load test) ( 24651765) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		23 interacting genes: CBX4 CERT1 DAXX EHHADH FXR2 HGS HID1 HTT NTAQ1 PIAS1 PIAS2 PIAS3 PIN1 PRKAG1 PRKAR1A PSMA1 RANBP9 UBASH3A UBE2I UGP2 VTA1 ZDHHC17 ZMYM5	380 interacting genes: AARD ACD ACOT13 ACTB ACTG1 ACTN2 ACY1 ADAMTSL4 AGR2 AGR3 AIMP2 AKIRIN2 AMOT AMOTL2 AMPD2 ANKRD11 ANKRD36B AOC1 APIP ARID4B ARL6IP1 ASL ATP6V1G1 BANF2 BCL2L2-PABPN1 BEND5 BIRC7 BLMH BLOC1S6 BLZF1 BOLA2 BOLA2B BORCS6 BPIFB3 BTBD1 BTBD2 BTBD6 C1orf50 CAMK2A CAPN3 CARD9 CASP6 CAVIN4 CBFA2T2 CBS CBY2 CCDC102B CCDC115 CCDC152 CCDC184 CCDC197 CCHCR1 CCNB1IP1 CD22 CDA CDCA8 CDK2AP1 CDKN2AIPNL CDR2 CENPP CEP170B CEP55 CEP70 CEP85 CGGBP1 CHCHD3 CHMP4A CMTM5 COG6 COIL CRYAA CRYAA2 CSNK2B CT45A1 CTAG1A CTAG1B CTBP1 CTH CUEDC1 CUTC CYSRT1 DAB1 DCTPP1 DEUP1 DHPS DNAL4 DNM2 DYNLT1 EDARADD EGLN3 EIF2B1 EIF4G1 EMILIN3 ENOX2 EP400 EPN3 ETV6 EXOSC8 FAM136A FAM72A FAM72D FKBP6 FTH1 FTL GADD45GIP1 GAS7 GCSAML GFAP GMCL1 GMDS GNG3 GNMT GNPDA2 GOLGA2 GOLGA6L9 GPX7 GRAMD4 GSTA4 GSTO2 GTF2H2C H2AP HAUS8 HBQ1 HBZ HEATR5A HGD HIGD1C HMG20A HOMER3 HOXB6 HPRT1 HSD17B14 HSF2BP HSPE1 HUS1 IKZF3 IL16 IL31 INCA1 ISCA2 ITGB3BP JAKMIP2 JUP KASH5 KATNBL1 KCNH1 KCTD1 KCTD10 KCTD13 KCTD15 KCTD21 KCTD4 KCTD6 KCTD7 KCTD9 KEAP1 KIF21B KLHL12 KLHL2 KLHL20 KRT27 KRT31 KRTAP10-5 KRTAP10-7 KRTAP19-2 KRTAP19-6 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-1 KRTAP9-2 KRTAP9-4 KRTAP9-8 L3MBTL3 LCE1C LCE1D LCE1E LCE1F LCE2C LCE5A LDB2 LENG1 LGALS2 LGALS9B LIN7B LMNA LMO1 LMO2 LMO3 LNX2 LONRF1 LRIF1 LRRC73 LSM12 LSM14B LZTFL1 LZTS1 LZTS2 MAB21L3 MAD1L1 MAGEA11 MAGEA12 MAGEA2 MAGEA2B MALSU1 MARCHF10 MATN4 MDFI MED22 MIF MIF4GD MIOS MIPOL1 MIS18A MITD1 MOB2 MORN3 MPLKIP MRFAP1L1 MRPL12 MTHFD2L MTUS2 MVP MXRA8 MYD88 N4BP3 NAB2 NADSYN1 NAGK NCOA5 NDUFAB1 NECAB2 NME1 NPL NR5A1 NT5C1A NTAN1 NUDT14 NUDT16L1 NUDT21 OOEP PAK5 PCBD1 PFDN5 PGPEP1 PIH1D2 PLA2G10 PLCD1 PLEKHB2 PLEKHJ1 PNMA1 PNMA2 PNMA5 POLR2J POMC PPCDC PPM1K PPP1R27 PRKAR1B PRMT1 PRMT5 PRPS2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRTFDC1 PSMB5 PSME3 PTS PYCR3 PYGM RAB42 RABAC1 RASAL3 RBBP8 RBM20 RBM45 RBM48 RBPMS RD3 REEP6 RHOQ RILPL1 RNF138 RNF4 ROPN1 RPIA RUSC1 S100A11 SAP18 SARS2 SAT1 SCARA5 SELENOV SEPTIN14 SEPTIN3 SFN SH3GLB2 SIAH1 SIKE1 SIVA1 SLAIN1 SLC15A2 SLPI SMAP1 SMN1 SNAP29 SNRPD3 SPANXB1 SPATA32 SPDYE4 SPINDOC SPRYD7 SSNA1 SSX2IP STH STMN2 STN1 STX11 SYCE1L SYNGAP1 TAX1BP1 TBX15 TCL1A TCP10L TEKT1 TEPSIN THAP1 THAP6 THAP7 THG1L TICAM2 TIFA TLE5 TMEM239 TNFAIP1 TNIP3 TNR TOLLIP TRAF1 TRAF3 TRAF5 TRIM23 TRIM27 TRIM32 TRIM5 TRIM54 TRIM69 TRIM73 TRIM9 TRIP13 TSC22D1 TSN TSNAX UBR1 UBR2 UFC1 UNKL VAC14 VCP VDR VPS37C VXN XIAP ZBED1 ZBTB8A ZBTB8B ZC2HC1C ZCCHC17 ZNF165 ZNF341 ZNF436 ZNF511 ZNF618 ZSCAN16 ZSCAN32
Entrez ID		875	55093
HPRD ID		01994	07653
Ensembl ID		ENSG00000160200	ENSG00000156795
Uniprot IDs		B7Z2D6 P0DN79 P35520 Q9NTF0	A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8
PDB IDs		1JBQ 1M54 4COO 4L0D 4L27 4L28 4L3V 4PCU 4UUU 5MMS	3C9Q 4W79 6KGJ
Enriched GO Terms of Interacting Partners?
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