LUC7L2 and PEA15

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LUC7L2	PEA15
Description		LUC7 like 2, pre-mRNA splicing factor	proliferation and apoptosis adaptor protein 15
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP Nuclear Speck U2-type Prespliceosome	Nucleoplasm Cytosol Microtubule Associated Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding	Protein Binding
	Biological Process	MRNA Splice Site Selection	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways			RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132)
Interacting Genes		55 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2	40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		51631	8682
HPRD ID		17456	04579
Ensembl ID		ENSG00000146963	ENSG00000162734
Uniprot IDs		Q9Y383	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs			4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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