LUC7L2 and CADPS

Data Source:
HPRD (two hybrid)

		LUC7L2	CADPS
Description		LUC7 like 2, pre-mRNA splicing factor	calcium dependent secretion activator
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP Nuclear Speck U2-type Prespliceosome	Cytosol Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	MRNA Splice Site Selection	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis
Pathways
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132)	Adult body size ( 32376654) Autism spectrum disorder ( 30804558) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast size ( 22747683 27182965) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Economic and political preferences (environmentalism) ( 22566634) Fasting plasma glucose ( 31932636) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Meat-related diet ( 32066663) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) Processed meat consumption ( 32066663) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)
Interacting Genes		55 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2	43 interacting genes: ACTN3 ANKS1A AURKC C17orf67 CABP5 CCDC120 CCDC185 DMD DNAJC5 DRD2 FAM161A FAM90A1 FAM9B FANCL FOXD2 GADD45GIP1 GPANK1 GSE1 HDAC4 HOXB5 HOXC8 KANK2 KIAA1549 LNX1 LUC7L2 OLIG3 PIP5K1A PNMA5 PRPF18 SDCBP SEC23A SH2D4A SHFL TCL1A TENT2 TRIM55 TRIM63 TSEN2 TTLL10 USP2 ZFC3H1 ZNF572 ZNF688
Entrez ID		51631	8618
HPRD ID		17456	05236
Ensembl ID		ENSG00000146963	ENSG00000163618
Uniprot IDs		Q9Y383	F1T0E5 Q9ULU8
PDB IDs			1WI1
Enriched GO Terms of Interacting Partners?
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