KLF7 and FBXO38

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		KLF7	FBXO38
Description		Kruppel like factor 7	F-box protein 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Nucleus Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Zinc Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Axonogenesis Axon Guidance Glucose Homeostasis Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Dendrite Morphogenesis Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Adipose Tissue Development	Adaptive Immune Response Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Neuron Projection Development SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Diastolic blood pressure ( 30224653) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Lachrymal/Salivary gland lesion in type 1 autoimmune pancreatitis ( 25985088) Platelet distribution width ( 32888494) Red blood cell count ( 32888494 27863252) Self-rated health ( 27864402) Smoking status (ever vs never smokers) ( 30643258) Urinary albumin excretion (no hypertensive medication) ( 30220432)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Lung function (FEV1/FVC) ( 31453325) Lung function (FEV1/FVC) variance ( 31453325) Mean reticulocyte volume ( 32888494) Periodontal microbiota ( 22699663) Zinc levels ( 26025379)
Interacting Genes		2 interacting genes: APP FBXO38	8 interacting genes: ABL2 APP CREBBP KLF7 PPM1G RING1 SOX30 SUMO2
Entrez ID		8609	81545
HPRD ID		07279	09775
Ensembl ID		ENSG00000118263	ENSG00000145868
Uniprot IDs		A0A024R3X8 O75840	Q6AZE0 Q6PIJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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