FBXO38 and KLF7

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		FBXO38	KLF7
Description		F-box protein 38	Kruppel like factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Zinc Ion Binding
	Biological Process	Adaptive Immune Response Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Neuron Projection Development SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Axonogenesis Axon Guidance Glucose Homeostasis Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Dendrite Morphogenesis Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Adipose Tissue Development
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Lung function (FEV1/FVC) ( 31453325) Lung function (FEV1/FVC) variance ( 31453325) Mean reticulocyte volume ( 32888494) Periodontal microbiota ( 22699663) Zinc levels ( 26025379)	Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Diastolic blood pressure ( 30224653) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Lachrymal/Salivary gland lesion in type 1 autoimmune pancreatitis ( 25985088) Platelet distribution width ( 32888494) Red blood cell count ( 32888494 27863252) Self-rated health ( 27864402) Smoking status (ever vs never smokers) ( 30643258) Urinary albumin excretion (no hypertensive medication) ( 30220432)
Interacting Genes		8 interacting genes: ABL2 APP CREBBP KLF7 PPM1G RING1 SOX30 SUMO2	2 interacting genes: APP FBXO38
Entrez ID		81545	8609
HPRD ID		09775	07279
Ensembl ID		ENSG00000145868	ENSG00000118263
Uniprot IDs		Q6AZE0 Q6PIJ6	A0A024R3X8 O75840
PDB IDs
Enriched GO Terms of Interacting Partners?
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