FBXO38 and SOX30

Data Source:
BioGRID (two hybrid)

		FBXO38	SOX30
Description		F-box protein 38	SRY-box transcription factor 30
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Chromatin Nucleus Cytoplasm Chromocenter
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Adaptive Immune Response Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Neuron Projection Development SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II Proacrosomal Vesicle Fusion
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Lung function (FEV1/FVC) ( 31453325) Lung function (FEV1/FVC) variance ( 31453325) Mean reticulocyte volume ( 32888494) Periodontal microbiota ( 22699663) Zinc levels ( 26025379)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		8 interacting genes: ABL2 APP CREBBP KLF7 PPM1G RING1 SOX30 SUMO2	18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FHL2 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		81545	11063
HPRD ID		09775	09461
Ensembl ID		ENSG00000145868	ENSG00000039600
Uniprot IDs		Q6AZE0 Q6PIJ6	B4DXW7 O94993
PDB IDs			7JJK
Enriched GO Terms of Interacting Partners?
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