PRPF18 and GOLGA6L9

Data Source:
BioGRID (two hybrid)

		PRPF18	GOLGA6L9
Description		pre-mRNA processing factor 18	golgin A6 family like 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex U5 SnRNP Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Post-spliceosomal Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA Processing RNA Splicing Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) ( 24025145) Craniofacial microsomia ( 26853712) Lupus nephritis in systemic lupus erythematosus ( 24925725) Post bronchodilator FEV1/FVC ratio ( 26634245) Skin pigmentation ( 28300201)	Tourette syndrome ( 30818990)
Interacting Genes		81 interacting genes: AGTRAP AMOTL2 AP2M1 ASCC2 BEGAIN BICD2 BLZF1 CADPS CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC150 CCDC57 CCNC CDR2 CEP70 CSRNP1 DVL3 EFHC2 EVI5L FERMT3 FSD2 GAS8 GCC1 GOLGA2 GOLGA6L9 GPBP1 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKBKG IKZF1 KANK2 KCTD7 KIFC3 KRT31 KRT34 KRT35 KRT39 KRT40 LDOC1 LZTS1 LZTS2 MCC MDFI MEOX2 MTUS2 NACC1 NECAB2 NINL NUTM1 NUTM2F OSBPL3 PDE9A PFDN5 PIBF1 PICK1 PLEKHG4 PNMA1 PPIH PRKAR1B RHOU RINT1 SCHIP1 SPRED1 STX11 TRAF2 TRIM23 TRIM27 TRIM54 TSNAX TSNAXIP1 UBXN11 ZNF526 ZNF639 ZRANB1	215 interacting genes: ANKRD11 ARHGAP9 ASXL1 ATP6V1G1 ATPAF2 ATXN7L2 AVPI1 BAG6 BAHD1 BANP BCL6B BHLHA9 BYSL C1orf109 C1orf35 C22orf15 C3 CABP2 CATIP CAVIN3 CBX8 CCDC116 CCDC120 CCDC146 CCDC185 CCDC187 CCHCR1 CDC37 CDC73 CDK18 CEP72 CEP95 CNNM3 CWF19L2 DAXX DEF6 DENND5A DES DOCK2 DPF2 DUSP26 EAF1 EIF3D ENKD1 FAAP20 FAM107A FAM110A FAM161A FAM161B FAM207A FBXO28 FEM1A FLYWCH1 FXN GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 GTF2B HAPLN2 HBZ HDAC4 HDAC7 HGS HOXB5 HOXB9 HOXC8 IL16 INO80B ISCU JMY JRK KANK2 KCTD9 KLHL35 KRT1 KRT75 LAGE3 LENG1 LGALS4 LMO3 LMO4 LYSMD1 M1AP MAB21L2 MBD3 MBD3L2 MFAP1 MOS MRPL11 MYOZ3 NAB2 NDUFAF3 NSMF NTAQ1 NXF1 NXT2 ORC1 PATZ1 PCDHB14 PHF1 PIN1 PKN1 PNMA5 POLL POLR1C POU6F2 PPP1R18 PRKAB2 PRPF18 PRPF31 PWWP2B RANBP3L RASSF10 RIN1 RLN1 RNF39 RNPS1 RTP5 SCAND1 SCNM1 SH2D4A SHC3 SLIRP SMARCD1 SMARCE1 SNAI1 SSX5 STAMBPL1 STK25 SUOX SUV39H1 SUV39H2 TACO1 TBC1D30 TCEANC TEAD4 THAP7 TJAP1 TLE5 TLX3 TMSB4X TPRX1 TRAF3IP3 TRAF4 TRIM14 TSEN54 TSFM TSGA10IP TSPYL4 TTC23 TXN2 TYK2 UBASH3A UBL4B UBTFL1 USHBP1 USP2 VEZF1 WDR25 ZBTB16 ZBTB24 ZFHX3 ZFP1 ZGPAT ZKSCAN3 ZMAT2 ZNF124 ZNF155 ZNF165 ZNF17 ZNF20 ZNF205 ZNF230 ZNF250 ZNF264 ZNF32 ZNF329 ZNF35 ZNF410 ZNF414 ZNF417 ZNF438 ZNF444 ZNF446 ZNF479 ZNF48 ZNF490 ZNF497 ZNF524 ZNF552 ZNF557 ZNF574 ZNF578 ZNF580 ZNF581 ZNF587 ZNF599 ZNF624 ZNF628 ZNF629 ZNF648 ZNF669 ZNF696 ZNF764 ZNF785 ZNF792 ZNF80 ZNF835 ZNF837 ZNF844 ZNHIT1 ZSCAN23 ZSCAN26
Entrez ID		8559	440295
HPRD ID		05407
Ensembl ID		ENSG00000165630	ENSG00000197978
Uniprot IDs		Q99633	A6NEM1
PDB IDs		2DK4
Enriched GO Terms of Interacting Partners?
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