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GOLGA6L9 and HDAC7
Data Source:
BioGRID
(two hybrid)
GOLGA6L9
HDAC7
Description
golgin A6 family like 9
histone deacetylase 7
Image
No pdb structure
GO Annotations
Cellular Component
Histone Deacetylase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Protein Kinase C Binding
Protein Binding
Protein Kinase Binding
NAD-dependent Histone Deacetylase Activity (H3-K14 Specific)
Protein Deacetylase Activity
Activating Transcription Factor Binding
Metal Ion Binding
Repressing Transcription Factor Binding
14-3-3 Protein Binding
Biological Process
Protein Deacetylation
Negative Regulation Of Interleukin-2 Production
Negative Regulation Of Osteoblast Differentiation
Histone H3 Deacetylation
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of NIK/NF-kappaB Signaling
Pathways
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
SUMOylation of DNA damage response and repair proteins
Notch-HLH transcription pathway
Regulation of PTEN gene transcription
Drugs
Trichostatin A
Belinostat
Panobinostat
Diseases
GWAS
Tourette syndrome (
30818990
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
31361310
30929738
32296059
)
Asthma (adult onset) (
31036433
30929738
)
Bipolar disorder (
31043756
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Conjunctival UV autofluorescence (CUVAF) (
25590795
)
Diastolic blood pressure (
27841878
)
Inflammatory bowel disease (
28067908
)
Lymphocyte counts (
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean platelet volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Monocyte count (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Obesity-related traits (
23251661
)
Platelet count (
32888494
27863252
)
Platelet distribution width (
32888494
)
Plateletcrit (
32888494
27863252
)
Primary sclerosing cholangitis (
23603763
)
Systolic blood pressure (
27841878
)
Ulcerative colitis (
28067908
)
Urate levels (
23263486
)
White blood cell count (
32888494
)
Interacting Genes
215 interacting genes:
ANKRD11
ARHGAP9
ASXL1
ATP6V1G1
ATPAF2
ATXN7L2
AVPI1
BAG6
BAHD1
BANP
BCL6B
BHLHA9
BYSL
C1orf109
C1orf35
C22orf15
C3
CABP2
CATIP
CAVIN3
CBX8
CCDC116
CCDC120
CCDC146
CCDC185
CCDC187
CCHCR1
CDC37
CDC73
CDK18
CEP72
CEP95
CNNM3
CWF19L2
DAXX
DEF6
DENND5A
DES
DOCK2
DPF2
DUSP26
EAF1
EIF3D
ENKD1
FAAP20
FAM107A
FAM110A
FAM161A
FAM161B
FAM207A
FBXO28
FEM1A
FLYWCH1
FXN
GADD45GIP1
GAS2L2
GEM
GLIS2
GPANK1
GTF2B
HAPLN2
HBZ
HDAC4
HDAC7
HGS
HOXB5
HOXB9
HOXC8
IL16
INO80B
ISCU
JMY
JRK
KANK2
KCTD9
KLHL35
KRT1
KRT75
LAGE3
LENG1
LGALS4
LMO3
LMO4
LYSMD1
M1AP
MAB21L2
MBD3
MBD3L2
MFAP1
MOS
MRPL11
MYOZ3
NAB2
NDUFAF3
NSMF
NTAQ1
NXF1
NXT2
ORC1
PATZ1
PCDHB14
PHF1
PIN1
PKN1
PNMA5
POLL
POLR1C
POU6F2
PPP1R18
PRKAB2
PRPF18
PRPF31
PWWP2B
RANBP3L
RASSF10
RIN1
RLN1
RNF39
RNPS1
RTP5
SCAND1
SCNM1
SH2D4A
SHC3
SLIRP
SMARCD1
SMARCE1
SNAI1
SSX5
STAMBPL1
STK25
SUOX
SUV39H1
SUV39H2
TACO1
TBC1D30
TCEANC
TEAD4
THAP7
TJAP1
TLE5
TLX3
TMSB4X
TPRX1
TRAF3IP3
TRAF4
TRIM14
TSEN54
TSFM
TSGA10IP
TSPYL4
TTC23
TXN2
TYK2
UBASH3A
UBL4B
UBTFL1
USHBP1
USP2
VEZF1
WDR25
ZBTB16
ZBTB24
ZFHX3
ZFP1
ZGPAT
ZKSCAN3
ZMAT2
ZNF124
ZNF155
ZNF165
ZNF17
ZNF20
ZNF205
ZNF230
ZNF250
ZNF264
ZNF32
ZNF329
ZNF35
ZNF410
ZNF414
ZNF417
ZNF438
ZNF444
ZNF446
ZNF479
ZNF48
ZNF490
ZNF497
ZNF524
ZNF552
ZNF557
ZNF574
ZNF578
ZNF580
ZNF581
ZNF587
ZNF599
ZNF624
ZNF628
ZNF629
ZNF648
ZNF669
ZNF696
ZNF764
ZNF785
ZNF792
ZNF80
ZNF835
ZNF837
ZNF844
ZNHIT1
ZSCAN23
ZSCAN26
59 interacting genes:
ACOT11
ACTN4
ANTKMT
ARID5A
BCL6
BRWD1
C3orf36
CALCOCO2
CASP8
CDC42
CENPQ
DDIT4L
EDNRA
EGFR
ESM1
GNG12
GNMT
GOLGA6L9
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
KAT5
KLF16
KRBA2
LDB2
MARK2
MARK3
MEF2A
MEF2C
MEOX2
MIEN1
NCOR2
NME4
NRIP2
PATJ
PHC2
PPARD
PPP1R16A
PRKD1
PRKD2
RAC1
RAC2
RAC3
REL
RIPPLY1
RRAS2
RUNX2
SIN3A
SLC16A3
SOGA1
TIAF1
UBE2I
UBL3
YPEL3
YWHAG
YWHAQ
ZBTB16
Entrez ID
440295
51564
HPRD ID
09133
Ensembl ID
ENSG00000197978
ENSG00000061273
Uniprot IDs
A6NEM1
Q8WUI4
PDB IDs
3C0Y
3C0Z
3C10
3ZNR
3ZNS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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