PRPF18 and NUTM2F

Data Source:
BioGRID (two hybrid)

		PRPF18	NUTM2F
Description		pre-mRNA processing factor 18	NUT family member 2F
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex U5 SnRNP Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Post-spliceosomal Complex
	Molecular Function	Protein Binding
	Biological Process	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA Processing RNA Splicing Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) ( 24025145) Craniofacial microsomia ( 26853712) Lupus nephritis in systemic lupus erythematosus ( 24925725) Post bronchodilator FEV1/FVC ratio ( 26634245) Skin pigmentation ( 28300201)	Body mass index ( 28892062) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
Interacting Genes		81 interacting genes: AGTRAP AMOTL2 AP2M1 ASCC2 BEGAIN BICD2 BLZF1 CADPS CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC150 CCDC57 CCNC CDR2 CEP70 CSRNP1 DVL3 EFHC2 EVI5L FERMT3 FSD2 GAS8 GCC1 GOLGA2 GOLGA6L9 GPBP1 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKBKG IKZF1 KANK2 KCTD7 KIFC3 KRT31 KRT34 KRT35 KRT39 KRT40 LDOC1 LZTS1 LZTS2 MCC MDFI MEOX2 MTUS2 NACC1 NECAB2 NINL NUTM1 NUTM2F OSBPL3 PDE9A PFDN5 PIBF1 PICK1 PLEKHG4 PNMA1 PPIH PRKAR1B RHOU RINT1 SCHIP1 SPRED1 STX11 TRAF2 TRIM23 TRIM27 TRIM54 TSNAX TSNAXIP1 UBXN11 ZNF526 ZNF639 ZRANB1	20 interacting genes: ANKS1A ATXN1L C1orf109 FADD GRB2 HGS LENG8 MORN4 NCK1 NCK2 NFYC OSTF1 PRPF18 RAD23A RBM47 SH3GL1 SH3RF1 VPS37C ZMYND10 ZNF148
Entrez ID		8559	54754
HPRD ID		05407	19318
Ensembl ID		ENSG00000165630	ENSG00000130950
Uniprot IDs		Q99633	A1L443
PDB IDs		2DK4
Enriched GO Terms of Interacting Partners?
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