PPFIA1 and MBIP

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		PPFIA1	MBIP
Description		PTPRF interacting protein alpha 1	MAP3K12 binding inhibitory protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Presynaptic Active Zone	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus Cytosol
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Neurotransmitter Secretion Glutamate Secretion Synapse Organization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Osmosensory Signaling MAPK Cascade Histone H3 Acetylation
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	HATs acetylate histones
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335)
Interacting Genes		31 interacting genes: AGTPBP1 CAGE1 CAST CCNH CDK18 CEP70 DNAJC5 DTNB DYNC1I2 ELOA ERC1 ERC2 FAM161A GAS8 GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5A PPP2R5D PTPRC PTPRD PTPRF PTPRS TNNT1 TXLNA YWHAG	44 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TXLNA TXLNB VPS28 VTA1 WDR5
Entrez ID		8500	51562
HPRD ID		11451	14368
Ensembl ID		ENSG00000131626	ENSG00000151332
Uniprot IDs		B3KVS8 Q13136	B2RCV0 Q9NS73
PDB IDs		1N7F
Enriched GO Terms of Interacting Partners?
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