MBIP and ING5

Data Source:
BioGRID (two hybrid)

		MBIP	ING5
Description		MAP3K12 binding inhibitory protein 1	inhibitor of growth family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus Cytosol	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Osmosensory Signaling MAPK Cascade Histone H3 Acetylation	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways		HATs acetylate histones	HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335)	Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		44 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TXLNA TXLNB VPS28 VTA1 WDR5	47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		51562	84289
HPRD ID		14368	16348
Ensembl ID		ENSG00000151332	ENSG00000168395
Uniprot IDs		B2RCV0 Q9NS73	A0A1B0GW41 Q8WYH8
PDB IDs			3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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