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MBIP and WDR5
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MBIP
WDR5
Description
MAP3K12 binding inhibitory protein 1
WD repeat domain 5
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Ada2/Gcn5/Ada3 Transcription Activator Complex
Nucleolus
Cytosol
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Ada2/Gcn5/Ada3 Transcription Activator Complex
Histone Methyltransferase Complex
MLL3/4 Complex
Set1C/COMPASS Complex
MLL1 Complex
Molecular Function
Protein Kinase Inhibitor Activity
Protein Binding
Identical Protein Binding
Protein Binding
Methylated Histone Binding
Histone Binding
Histone Methyltransferase Activity (H3-K4 Specific)
Biological Process
Osmosensory Signaling MAPK Cascade
Histone H3 Acetylation
Skeletal System Development
Neuron Projection Development
Post-translational Protein Modification
Histone H3 Acetylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K16 Acetylation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Gluconeogenesis
Histone H3-K4 Methylation
Positive Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Histone H3-K4 Methylation
Pathways
HATs acetylate histones
PKMTs methylate histone lysines
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Neddylation
Drugs
Diseases
GWAS
Hypertension (
31513605
)
Thyroid cancer (
22267200
)
Thyroid hormone levels (
23408906
)
Thyroid stimulating hormone levels (
32769997
25743335
)
Cerebrospinal fluid t-tau levels in normal cognition (
29274321
)
Intraocular pressure (
30591961
)
Interacting Genes
44 interacting genes:
BFSP2
CALM1
CCDC85B
CCNC
CEP63
COPS4
DGCR6
DGCR6L
DIP2A
DRC7
EPB41L3
EXOC8
FXR2
ING5
KAT14
KLC3
LIMS1
LMNB1
LMO2
LMO3
MAP3K12
MAPK6
MCM7
MIS18A
MOAP1
MYD88
NDEL1
NINL
PIK3R3
PLEKHF2
POLR1C
PPFIA1
RAP1GDS1
RAPGEF1
SMARCB1
STX11
TGIF2LY
TRIM55
TRIM63
TXLNA
TXLNB
VPS28
VTA1
WDR5
37 interacting genes:
ANAPC2
APP
ASH2L
ATN1
BBC3
BHLHE41
CHD8
FAM199X
H1-2
H3-4
H3C1
H4-16
HSF2
IKBKG
KANSL1
KANSL2
KMT2A
MARF1
MBIP
MDM4
MEOX2
MLLT1
NR2E3
PDE9A
POU5F1
PRMT5
PRNP
RBBP5
RUSC1-AS1
SRPK2
SRRM4
SSX2IP
TERF2IP
TP53
WWP2
ZBTB48
ZXDC
Entrez ID
51562
11091
HPRD ID
14368
10614
Ensembl ID
ENSG00000151332
ENSG00000196363
Uniprot IDs
B2RCV0
Q9NS73
P61964
PDB IDs
2CNX
2CO0
2G99
2G9A
2GNQ
2H13
2H14
2H68
2H6K
2H6N
2H6Q
2H9L
2H9M
2H9N
2H9P
2O9K
3EG6
3EMH
3MXX
3N0D
3N0E
3P4F
3PSL
3SMR
3UR4
3UVK
3UVL
3UVM
3UVN
3UVO
4A7J
4CY1
4CY2
4ERQ
4ERY
4ERZ
4ES0
4ESG
4EWR
4GM3
4GM8
4GM9
4GMB
4IA9
4O45
4QL1
4Y7R
5EAL
5EAM
5EAP
5EAR
5M23
5M25
5SXM
5VFC
6BYN
6D9X
6DAI
6DAK
6DAR
6DAS
6DY7
6DYA
6E1Y
6E1Z
6E22
6E23
6IAM
6KIU
6KIV
6KIW
6KIX
6KIZ
6OFZ
6OI0
6OI1
6OI2
6OI3
6PG3
6PG4
6PG5
6PG6
6PG7
6PG8
6PG9
6PGA
6PGB
6PGC
6PGD
6PGE
6PGF
6PWV
6PWW
6U5M
6U5Y
6U6W
6U80
6U8B
6U8L
6U8O
6UCS
6UFX
6UHY
6UHZ
6UIF
6UIK
6UJ4
6UJH
6UJJ
6UJL
6UOZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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