PIGY and PIGA

Data Source:
HPRD (in vivo)

		PIGY	PIGA
Description		phosphatidylinositol glycan anchor biosynthesis class Y	phosphatidylinositol glycan anchor biosynthesis class A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane	GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Cellular Response To Leukemia Inhibitory Factor
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)	Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases			Paroxysmal nocturnal hemoglobinuria (PNH)
GWAS		Bipolar disorder ( 22925353) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: ABCB4 ERG28 FBXO7 PIGA TMEM72	4 interacting genes: DPM2 PIGH PIGQ PIGY
Entrez ID		84992	5277
HPRD ID		17492	02410
Ensembl ID		ENSG00000255072	ENSG00000165195
Uniprot IDs		Q3MUY2	A0A2K4ZA02 P37287
PDB IDs
Enriched GO Terms of Interacting Partners?
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