PIGA and PIGY

Data Source:
HPRD (in vivo)

		PIGA	PIGY
Description		phosphatidylinositol glycan anchor biosynthesis class A	phosphatidylinositol glycan anchor biosynthesis class Y
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Cellular Response To Leukemia Inhibitory Factor	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)	Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases		Paroxysmal nocturnal hemoglobinuria (PNH)
GWAS			Bipolar disorder ( 22925353) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: DPM2 PIGH PIGQ PIGY	5 interacting genes: ABCB4 ERG28 FBXO7 PIGA TMEM72
Entrez ID		5277	84992
HPRD ID		02410	17492
Ensembl ID		ENSG00000165195	ENSG00000255072
Uniprot IDs		A0A2K4ZA02 P37287	Q3MUY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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