ADGRE2 and MTERF3

Data Source:
BioGRID (two hybrid)

		ADGRE2	MTERF3
Description		adhesion G protein-coupled receptor E2	mitochondrial transcription termination factor 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Leading Edge Membrane Ruffle Membrane	Mitochondrion Mitochondrial Outer Membrane Cytosol
	Molecular Function	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding
	Biological Process	Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis	Macroautophagy Negative Regulation Of Transcription, DNA-templated Mitochondrial Ribosome Assembly
Pathways		Class B/2 (Secretin family receptors)	PINK1-PRKN Mediated Mitophagy
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		19 interacting genes: AQP6 BIK CCDC107 CREB3L1 ELOVL4 ELOVL7 FAM209A FCER1G HSD17B13 KIR2DL3 LMNA MARCHF6 MFSD5 MMGT1 MTERF3 SAR1A SLC7A14 TLCD4 TMEM80	28 interacting genes: ADGRE2 AGTRAP APOC1 APP ARL6IP1 CACFD1 CMTM5 ERG28 FADS6 FUNDC1 GPR108 HIGD1C MAL2 MIR34B PBX3 RHBDD2 SCAMP1 SLC17A9 SLC2A5 SLC50A1 STX8 SYNGR1 SYP TMEM14C UPF2 YIF1A ZDHHC21 ZFPL1
Entrez ID		30817	51001
HPRD ID		07308	10823
Ensembl ID		ENSG00000127507	ENSG00000156469
Uniprot IDs		A0JNV7 Q9UHX3	E5RIK9 Q96E29
PDB IDs		2BO2 2BOU 2BOX	3M66
Enriched GO Terms of Interacting Partners?
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