ADGRE2 and MMGT1

Data Source:
BioGRID (two hybrid)

		ADGRE2	MMGT1
Description		adhesion G protein-coupled receptor E2	membrane magnesium transporter 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Leading Edge Membrane Ruffle Membrane	Golgi Membrane Early Endosome Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Early Endosome Membrane EMC Complex
	Molecular Function	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding	Protein Binding Cobalt Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity
	Biological Process	Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis	Cobalt Ion Transport Copper Ion Transport Magnesium Ion Transport Iron Ion Transmembrane Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport
Pathways		Class B/2 (Secretin family receptors)	Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		19 interacting genes: AQP6 BIK CCDC107 CREB3L1 ELOVL4 ELOVL7 FAM209A FCER1G HSD17B13 KIR2DL3 LMNA MARCHF6 MFSD5 MMGT1 MTERF3 SAR1A SLC7A14 TLCD4 TMEM80	51 interacting genes: ADGRE2 AGR3 ANKRD46 APP C4orf3 C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MFSD3 MFSD5 MS4A13 NDUFA3 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC35B4 SLC35E4 SLC38A7 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A
Entrez ID		30817	93380
HPRD ID		07308	06626
Ensembl ID		ENSG00000127507	ENSG00000169446
Uniprot IDs		A0JNV7 Q9UHX3	Q8N4V1
PDB IDs		2BO2 2BOU 2BOX	6WW7 6Z3W
Enriched GO Terms of Interacting Partners?
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