PPFIBP2 and PPFIA1

Data Source:
HPRD (in vivo, in vitro)

		PPFIBP2	PPFIA1
Description		PPFIA binding protein 2	PTPRF interacting protein alpha 1
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GO Annotations	Cellular Component	Extracellular Space Cytosol Presynaptic Active Zone	Cytoplasm Cytosol Focal Adhesion Presynaptic Active Zone
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Neuromuscular Junction Development Synapse Organization	Cell-matrix Adhesion Signal Transduction Neurotransmitter Secretion Glutamate Secretion Synapse Organization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		Receptor-type tyrosine-protein phosphatases	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Cutaneous melanoma or hair colour ( 32341527) Hair color ( 29662168) Malaria ( 31844061) Prostate cancer ( 29892016 26443449) Prostate cancer (advanced) ( 29892016)	Coronary artery disease ( 29212778) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		12 interacting genes: APP CLK1 CRK CRKL DTNB HSF4 PPFIA1 PPFIA2 PPFIA3 PRNP PTPRC TSG101	31 interacting genes: AGTPBP1 CAGE1 CAST CCNH CDK18 CEP70 DNAJC5 DTNB DYNC1I2 ELOA ERC1 ERC2 FAM161A GAS8 GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5A PPP2R5D PTPRC PTPRD PTPRF PTPRS TNNT1 TXLNA YWHAG
Entrez ID		8495	8500
HPRD ID		04391	11451
Ensembl ID		ENSG00000166387	ENSG00000131626
Uniprot IDs		Q8ND30	B3KVS8 Q13136
PDB IDs		3QH9	1N7F
Enriched GO Terms of Interacting Partners?
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