PPFIBP2 and PPFIA2

Data Source:
HPRD (in vitro)

		PPFIBP2	PPFIA2
Description		PPFIA binding protein 2	PTPRF interacting protein alpha 2
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GO Annotations	Cellular Component	Extracellular Space Cytosol Presynaptic Active Zone	Cytoplasm Cytosol Cell Surface Axon Dendritic Spine Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Protein Binding Structural Constituent Of Presynapse
	Biological Process	Neuromuscular Junction Development Synapse Organization	Cell-matrix Adhesion Neurotransmitter Secretion Glutamate Secretion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Receptor-type tyrosine-protein phosphatases	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Cutaneous melanoma or hair colour ( 32341527) Hair color ( 29662168) Malaria ( 31844061) Prostate cancer ( 29892016 26443449) Prostate cancer (advanced) ( 29892016)	Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)
Interacting Genes		12 interacting genes: APP CLK1 CRK CRKL DTNB HSF4 PPFIA1 PPFIA2 PPFIA3 PRNP PTPRC TSG101	13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS
Entrez ID		8495	8499
HPRD ID		04391	04392
Ensembl ID		ENSG00000166387	ENSG00000139220
Uniprot IDs		Q8ND30	B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62
PDB IDs		3QH9	3TAC 3TAD 6IUH
Enriched GO Terms of Interacting Partners?
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