ZC3H10 and NFYA

Data Source:
BioGRID (two hybrid, two hybrid)

		ZC3H10	NFYA
Description		zinc finger CCCH-type containing 10	nuclear transcription factor Y subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Binding Protein Binding MiRNA Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways			PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Mean spheric corpuscular volume ( 32888494) White blood cell count ( 27863252)
Interacting Genes		46 interacting genes: AOC1 APPBP2 ARID5A ATXN1 BOLL C10orf55 C19orf54 CRX DAB1 DAZAP2 FAM168B FOSB FOXH1 HIVEP1 INTS11 KLHDC7B KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MIR143 MSX2 NCS1 NFYA OTX2 OXER1 PIAS2 PICALM PLA2G10 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E RBM38 RBPMS RBPMS2 RNF4 STAM2 TENT5A TENT5B TEX37 UBE2I ZNF34	48 interacting genes: APP APPBP2 ATF6 ATF6B ATXN1 BANP BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 DVL3 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 POU3F2 PWP1 QRICH1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 UBL5 USF1 USF2 VEZF1 ZC3H10 ZHX1 ZHX2 ZHX3
Entrez ID		84872	4800
HPRD ID		07860	01793
Ensembl ID		ENSG00000135482	ENSG00000001167
Uniprot IDs		Q96K80	A0A024RD22 P23511
PDB IDs			4AWL 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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