NFYA and LUC7L2

Data Source:
BioGRID (two hybrid, two hybrid)

		NFYA	LUC7L2
Description		nuclear transcription factor Y subunit alpha	LUC7 like 2, pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex	U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Binding MRNA Binding Protein Binding Enzyme Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process	MRNA Splice Site Selection
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) White blood cell count ( 27863252)	Diisocyanate-induced asthma ( 25918132)
Interacting Genes		48 interacting genes: APP APPBP2 ATF6 ATF6B ATXN1 BANP BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 DVL3 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 POU3F2 PWP1 QRICH1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 UBL5 USF1 USF2 VEZF1 ZC3H10 ZHX1 ZHX2 ZHX3	55 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2
Entrez ID		4800	51631
HPRD ID		01793	17456
Ensembl ID		ENSG00000001167	ENSG00000146963
Uniprot IDs		A0A024RD22 P23511	Q9Y383
PDB IDs		4AWL 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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