TRIM52 and RNF114

Data Source:
BioGRID (two hybrid)

		TRIM52	RNF114
Description		tripartite motif containing 52	ring finger protein 114
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Body	Nucleus Cytosol Plasma Membrane
	Molecular Function	Transcription Coactivator Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Protein Autoubiquitination	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		5 interacting genes: APP NEDD4 RNF114 RNF126 TRIM41	29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1
Entrez ID		84851	55905
HPRD ID		10283	10329
Ensembl ID		ENSG00000183718	ENSG00000124226
Uniprot IDs		Q96A61	Q9Y508
PDB IDs
Enriched GO Terms of Interacting Partners?
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