USP32 and TRIM46

Data Source:
BioGRID (two hybrid)

		USP32	TRIM46
Description		ubiquitin specific peptidase 32	tripartite motif containing 46
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Membrane	Cytoskeleton Axon Initial Segment Main Axon Axon Cytoplasm Proximal Neuron Projection
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Calcium Ion Binding Protein Binding Cysteine-type Peptidase Activity	Zinc Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation	Microtubule Bundle Formation Neuron Migration Axonogenesis Negative Regulation Of Axon Extension Anterograde Synaptic Vesicle Transport Protein Localization To Axon Positive Regulation Of Anterograde Dense Core Granule Transport Regulation Of Cellular Protein Localization
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 31511532) Serum uric acid levels ( 30993211) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31985003 31578528 23263486) Urinary albumin-to-creatinine ratio ( 31511532) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		11 interacting genes: ANKRD29 MEOX2 MTNR1A NCK2 RBCK1 RNF144A TRIM3 TRIM46 TRIM74 UBC ZDHHC17	20 interacting genes: AK5 APP BRCA1 CBLC MDM4 MTNR1B OTUD6A RNF125 RNF7 TK1 TRIM9 TSG101 UBE2D2 UBE2U UBE2Z UCHL5 USP1 USP15 USP2 USP32
Entrez ID		84669	80128
HPRD ID		07612	15563
Ensembl ID		ENSG00000170832	ENSG00000163462
Uniprot IDs		Q8NFA0	A0A087WUH1 B7Z4F9 F5GYK0 Q7Z4K8
PDB IDs
Enriched GO Terms of Interacting Partners?
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