TRIM46 and USP32

Data Source:
BioGRID (two hybrid)

		TRIM46	USP32
Description		tripartite motif containing 46	ubiquitin specific peptidase 32
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Axon Initial Segment Main Axon Axon Cytoplasm Proximal Neuron Projection	Golgi Apparatus Cytosol Membrane
	Molecular Function	Zinc Ion Binding	Thiol-dependent Ubiquitin-specific Protease Activity Calcium Ion Binding Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Microtubule Bundle Formation Neuron Migration Axonogenesis Negative Regulation Of Axon Extension Anterograde Synaptic Vesicle Transport Protein Localization To Axon Positive Regulation Of Anterograde Dense Core Granule Transport Regulation Of Cellular Protein Localization	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 31511532) Serum uric acid levels ( 30993211) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31985003 31578528 23263486) Urinary albumin-to-creatinine ratio ( 31511532) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		20 interacting genes: AK5 APP BRCA1 CBLC MDM4 MTNR1B OTUD6A RNF125 RNF7 TK1 TRIM9 TSG101 UBE2D2 UBE2U UBE2Z UCHL5 USP1 USP15 USP2 USP32	11 interacting genes: ANKRD29 MEOX2 MTNR1A NCK2 RBCK1 RNF144A TRIM3 TRIM46 TRIM74 UBC ZDHHC17
Entrez ID		80128	84669
HPRD ID		15563	07612
Ensembl ID		ENSG00000163462	ENSG00000170832
Uniprot IDs		A0A087WUH1 B7Z4F9 F5GYK0 Q7Z4K8	Q8NFA0
PDB IDs
Enriched GO Terms of Interacting Partners?
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