SPINK7 and GALNT10

Data Source:
BioGRID (affinity chromatography technology)

		SPINK7	GALNT10
Description		serine peptidase inhibitor Kazal type 7	polypeptide N-acetylgalactosaminyltransferase 10
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GO Annotations	Cellular Component	Extracellular Region	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Protein O-linked Glycosylation O-glycan Processing Protein Phosphopantetheinylation
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)	Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 21701570 25673413 23583978) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549)
Interacting Genes		8 interacting genes: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6	3 interacting genes: CNOT2 MUC1 MUC7
Entrez ID		84651	55568
HPRD ID		16850	12157
Ensembl ID		ENSG00000145879	ENSG00000164574
Uniprot IDs		P58062	Q86SR1
PDB IDs		2LEO	2D7I 2D7R
Enriched GO Terms of Interacting Partners?
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