SPINK7 and EPB42

		SPINK7	EPB42
Description		serine peptidase inhibitor Kazal type 7	erythrocyte membrane protein band 4.2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Cytoskeleton Plasma Membrane Cortical Cytoskeleton
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Protein-glutamine Gamma-glutamyltransferase Activity Structural Constituent Of Cytoskeleton Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Cell Morphogenesis Cytoskeleton Organization Regulation Of Cell Shape Peptide Cross-linking Protein Phosphopantetheinylation Hemoglobin Metabolic Process Erythrocyte Maturation Spleen Development Iron Ion Homeostasis
Pathways
Drugs
Diseases			Hereditary spherocytosis (SPH)
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		8 interacting genes: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6	13 interacting genes: ANK1 ANK2 BLOC1S4 CD47 DMTN EPB41 KRAS MAPK14 SLC4A1 SLC4A2 SPINK7 SPTAN1 STX12
Entrez ID		84651	2038
HPRD ID		16850	01517
Ensembl ID		ENSG00000145879	ENSG00000166947
Uniprot IDs		P58062	P16452
PDB IDs		2LEO
Enriched GO Terms of Interacting Partners?
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