GALNT10 and MUC7

Data Source:
HPRD (in vitro)

		GALNT10	MUC7
Description		polypeptide N-acetylgalactosaminyltransferase 10	mucin 7, secreted
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Golgi Lumen Plasma Membrane Extracellular Exosome
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein O-linked Glycosylation O-glycan Processing Protein Phosphopantetheinylation	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Killing Of Cells Of Other Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		O-linked glycosylation of mucins	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 21701570 25673413 23583978) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549)	Diabetic nephropathy in type 1 diabetes ( 31537649)
Interacting Genes		3 interacting genes: CNOT2 MUC1 MUC7	8 interacting genes: AMY1A GALNT10 GALNT12 GALNT14 HTN3 LTF PCGF1 SELL
Entrez ID		55568	4589
HPRD ID		12157	11759
Ensembl ID		ENSG00000164574	ENSG00000171195
Uniprot IDs		Q86SR1	Q8TAX7
PDB IDs		2D7I 2D7R
Enriched GO Terms of Interacting Partners?
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