SPINK7 and MT2A

		SPINK7	MT2A
Description		serine peptidase inhibitor Kazal type 7	metallothionein 2A
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GO Annotations	Cellular Component	Extracellular Region	Nucleus Cytoplasm Cytosol
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Cellular Copper Ion Homeostasis Cellular Zinc Ion Homeostasis Response To Metal Ion Detoxification Of Copper Ion Cellular Response To Interleukin-3 Cellular Response To Erythropoietin Negative Regulation Of Growth Interferon-gamma-mediated Signaling Pathway Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion
Pathways			Metallothioneins bind metals Metallothioneins bind metals Interferon gamma signaling
Drugs			Zinc Silver Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)
Interacting Genes		8 interacting genes: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6	19 interacting genes: ADAMTS4 ARF6 ASS1 BARD1 DHODH ECT2 EOLA1 HMGB1 JMJD1C LAMTOR5 MCPH1 PAXIP1 PRKD1 RCHY1 RIN3 SHBG SPINK7 TNS2 USP25
Entrez ID		84651	4502
HPRD ID		16850	08863
Ensembl ID		ENSG00000145879	ENSG00000125148
Uniprot IDs		P58062	P02795
PDB IDs		2LEO	1MHU 2MHU
Enriched GO Terms of Interacting Partners?
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