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LCE3D and CCN3
Data Source:
BioGRID
(two hybrid)
LCE3D
CCN3
Description
late cornified envelope 3D
cellular communication network factor 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Extracellular Region
Cytoplasm
Gap Junction
Axon
Dendrite
Extracellular Matrix
Neuronal Cell Body
Intracellular Membrane-bounded Organelle
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
Notch Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Growth Factor Activity
Heparin Binding
Biological Process
Cornification
Angiogenesis
Chondrocyte Differentiation
Cell Adhesion
Signal Transduction
Regulation Of Gene Expression
Fibroblast Migration
Negative Regulation Of Myotube Differentiation
Smooth Muscle Cell Migration
Negative Regulation Of Cell Growth
Cell Adhesion Mediated By Integrin
Endothelial Cell Chemotaxis
Type B Pancreatic Cell Proliferation
Positive Regulation Of Notch Signaling Pathway
Negative Regulation Of Insulin Secretion
Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Cell Chemotaxis
Negative Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of Cell Death
Hematopoietic Stem Cell Homeostasis
Endothelial Cell-cell Adhesion
Negative Regulation Of Monocyte Chemotaxis
Negative Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Chondrocyte Proliferation
Negative Regulation Of Sensory Perception Of Pain
Bone Regeneration
Pathways
Formation of the cornified envelope
Drugs
Insulin pork
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Asthma (
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Psoriasis (
25854761
20953190
23143594
19169255
)
Interacting Genes
55 interacting genes:
ADAMTSL4
ALPP
CCN3
CHIC2
CYSRT1
EFEMP1
EFEMP2
FBLN2
KPRP
KRT31
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP3-1
KRTAP3-2
KRTAP3-3
KRTAP4-1
KRTAP4-12
KRTAP4-2
KRTAP4-5
KRTAP5-3
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE2B
LCE2C
MDFI
NBPF19
NOTCH2NLA
PCSK5
RGS17
RGS20
SDC3
SPRY1
SPRY3
SRPK1
SRPK2
TENM4
TGFB1
TRIM42
TSPAN4
VWC2
29 interacting genes:
ADSL
ANKRD11
APOL6
C11orf87
CCN2
CDKN1A
COL8A1
DLL1
FAM90A1
FBLN1
FN1
FRS3
GJA1
HOXA1
IGF1
IGF2
INS
ITGAV
KRTAP5-6
LCE1A
LCE3D
NID2
NOTCH1
POLR2L
POU4F2
RECK
S100A4
TNIP3
ZNF330
Entrez ID
84648
4856
HPRD ID
17263
01291
Ensembl ID
ENSG00000163202
ENSG00000136999
Uniprot IDs
Q9BYE3
A0A024R9J4
P48745
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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