TTBK1 and CSN1S1

Data Source:
HPRD (in vitro)

		TTBK1	CSN1S1
Description		tau tubulin kinase 1	casein alpha s1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Neuronal Cell Body Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Tau Protein Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding
	Biological Process	Protein Phosphorylation Learning Or Memory Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Substantia Nigra Development Negative Regulation Of Protein Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Astrocyte Activation Positive Regulation Of Microglial Cell Activation Positive Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Cysteine-type Endopeptidase Activity	Response To Estradiol Response To Progesterone Transmembrane Transport Response To Dehydroepiandrosterone Response To 11-deoxycorticosterone
Pathways			Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Adult hearing difficulty ( 31564434) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Body size at age 10 ( 32376654) Diastolic blood pressure ( 29403010) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Hemoglobin ( 32888494) Mean arterial pressure ( 29403010) Pulse pressure ( 28739976) Red blood cell count ( 32888494) Systolic blood pressure ( 26390057 29403010 28739976)
Interacting Genes		5 interacting genes: CDK5R1 CSN1S1 MAP2 MAPT TUBB	11 interacting genes: CSNK2A1 CSNK2B HTRA2 PARK7 PLK1 PPM1J PRSS2 STK4 TOLLIP TTBK1 UBQLN2
Entrez ID		84630	1446
HPRD ID		11653	00280
Ensembl ID		ENSG00000146216	ENSG00000126545
Uniprot IDs		Q5TCY1	P47710
PDB IDs		4BTJ 4BTK 4BTM 4NFM 4NFN
Enriched GO Terms of Interacting Partners?
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